What is Crohn’s Disease? Is it Fatal?

Crohn’s disease is a form of inflammatory bowel illness (IBD). According to the Crohn’s & Colitis Foundation of America, up to 780,000 Americans suffer from the disease. 

To better understand Crohn’s disease, we need more study in this area. Researchers aren’t clear on how it originates, who is most likely to have it, or how to effectively manage it. Yet no cure exists despite enormous therapeutic progress over the previous three decades. So, what actually is Crohn’s disease? Is it fatal? Everything you need to know about Crohn’s disease is right here.

Crohn’s Disease

Crohn’s disease is a kind of intestinal inflammation (IBD). When your digestive system becomes inflamed, it can produce various symptoms, including nausea, vomiting, diarrhea, and exhaustion, as well as weight loss and malnutrition.

Crohn’s disease can induce inflammation in different parts of the digestive tract in different people, depending on their genetics. It is not uncommon for this inflammation to go into the bowel’s deeper layers.

Crohn’s disease is a chronic and life-threatening condition that can cause severe discomfort and even death.


This condition can have modest to severe signs and symptoms. They normally come on gradually, but there are instances when they appear out of nowhere. Periods without any symptoms are also possible (remission).

Signs and symptoms of the active illness include:

  • Diarrhea 
  • Fever
  • Fatigue
  • Constipation
  • Cramps in the abdomen
  • Bloody Stool
  • Reduced appetite 
  • Sores in the mouth
  • Decreased weight

Inflammation from a skin tunnel (fistula) causes pain and discharge in or around the anus. 

Severe symptoms of Crohn’s disease might include:

  • Inflammation of the liver or bile ducts
  • Skin, eyes, and joint inflammation
  • Kidney stones
  • Deficiency of iron (anemia)
  • Lack of growth or sexual development in youngsters


Crohn’s disease is still a mystery as to what causes it. Crohn’s disease had previously been linked to food and stress, but physicians now know that these variables can exacerbate, but not cause, the illness. Heredity and an immune system dysfunction are likely contributors to its development.


Because Crohn’s disease is more frequent in persons who have a family history of the illness, this suggests that genetics play a role. Most persons with Crohn’s disease, on the other hand, don’t have a family history of the condition.

Immune system

A virus or bacteria may cause Crohn’s disease, but scientists have yet to find a trigger. This is a possibility. Because of an aberrant immune reaction, the immune system also attacks your digestive tract as you fight off the invader bacterium.

Is Crohn’s Disease Fatal?

Crohn’s disease can cause serious and even life-threatening consequences if left untreated. These issues need to be treated carefully to avoid more problems. The only way to avoid these issues is to get the proper therapy. So consulting a Best Gastroenterologist in Rawalpindi on time is very important to get expert advice. 

Crohn’s disease can lead to serious consequences, such as the following:

Cancer of the Colon

According to a study, colorectal cancer, or cancer of the lining of the colon or rectum, is more common in those with IBD. People who have had Crohn’s disease for a decade or longer have an even greater risk.

Dysplasia (also known as early-stage aberrant cells) can occur due to chronic inflammation from untreated Crohn’s disease.


These are abnormal connections between your intestinal walls and other body sections, such as another organ or tissue. 

Fluid from your stomach or GI system can leak into other sections of your body, organs, or abdominal cavity if these tunnels develop. Sepsis, a life-threatening illness, can result from this.

If your GI system cannot absorb the nutrients your body requires, malnutrition may occur. In the long run, a deficiency in nutrients can be fatal. According to Crohn’s and Colitis UK, about one-fourth of those with Crohn’s disease will experience this consequence.

Obstruction in the Intestine

Your gastrointestinal system might become inflamed and scarred over time due to chronic inflammation. Intestinal strictures can result as a result of this. When your colon becomes completely blocked, there is a risk of tearing your colon.

Despite being the most prevalent consequence of Crohn’s disease, intestinal blockage still poses a life-threatening risk.

Colonic Perforation

Complications of Crohn’s disease might damage different parts of the intestinal wall. The following are some of the issues:

  • Persistent inflammation
  • Fistula
  • strictures

Some of these weak areas may rip or perforate with time. Bacteria and other substances from your intestines will be able to pour into your abdomen. Sepsis or blood poisoning can result from untreated or improperly managed peritonitis. Both of them are quite dangerous.

Toxic Megacolon 

Because of the inflammation and gas in your intestines, this syndrome arises when your bowels get so bloated that they can no longer contract.

Your colon might explode if you don’t release the pressure appropriately. Bacteria and other chemicals will be able to enter your abdomen and bloodstream due to this. If this isn’t taken care of promptly, it might lead to:

  • Shock
  • Internal hemorrhage
  • Sepsis

As far as Crohn’s disease complications go, this is extremely unusual. People with ulcerative colitis, another kind of IBD, are more likely to experience it.


People with Crohn’s disease are frequently plagued by health issues related to poor nutrition or malnourishment. This is because unhealthy intestines may be able to absorb nutrients better than inflamed ones.

Over time, this can lead to serious vitamin deficits, which can be life-threatening.

Crohn’s disease can be lethal if left untreated. This is because the persistent inflammation connected with this intestinal ailment can lead to several serious and even deadly consequences.

Most persons with Crohn’s disease will never have to deal with these issues. However, it is dependent on frequent and thorough therapy.

You should immediately contact a best Gastroenterologist in Islamabad if you experience any issues. It’s better to contact on time before it’s too late. You can Book an appointment with the Best Specialist through Marham.


1. Is it possible to die from Crohn’s disease?

Crohn’s disease is not lethal on its own. However, depending on the severity and location of the condition, it might have life-threatening consequences.

2. What is the mortality rate with Crohn’s disease?

Crohn’s disease had a death rate of 1.6% compared to a control mortality rate of 1% for people of the same age, gender, and practice. In Crohn’s disease patients, the risk of mortality was 73% greater than in the general population after accounting for factors such as age, gender, and smoking.

3. How can I tell if I have Crohn’s disease or IBS?

Having a bowel movement might alleviate symptoms that arise after a heavy meal or during times of stress. IBD causes anemia, bleeding, weight loss, and fever. 

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